EMB Antibody, Biotin conjugated

Datasheet

Code	CSB-PA754239LD01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) EMB Polyclonal antibody

Uniprot No.

Q6PCB8

Target Names

EMB

Alternative Names

Emb antibody; EMB_HUMAN antibody; Embigin antibody; Embigin homolog (mouse) antibody; embigin homolog antibody; MGC71745 antibody; OTTHUMP00000161812 antibody; OTTHUMP00000221477 antibody; OTTHUMP00000221478 antibody; OTTHUMP00000221479 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Embigin protein (285-327AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Plays a role in the outgrowth of motoneurons and in the formation of neuromuscular junctions. Following muscle denervation, promotes nerve terminal sprouting and the formation of additional acetylcholine receptor clusters at synaptic sites without affecting terminal Schwann cell number or morphology. Delays the retraction of terminal sprouts following re-innervation of denervated endplates. May play a role in targeting the monocarboxylate transporters SLC16A1 and SLC16A7 to the cell membrane.

Gene References into Functions

Study reports elevated expression of Embigin in pancreatic ductal adenocarcinoma and shows its novel functions in regulating cell proliferation, migration, and invasion. PMID: 25773908
embigin is regulated by HOXC8 and its loss plays an important role in the progression of breast tumors PMID: 26090721
Data show that Gp70 (embigin) was negative in all normal, adjacent non-neoplastic and PIN lesions and only a very small percentage of cases. PMID: 21787388
Reports the original cloning of the mouse embigin gene, referred to as gp70, from embryonal carcinoma cells. PMID: 2963822

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell junction, synapse.

Database Links

HGNC: 30465

OMIM: 615669

KEGG: hsa:133418

STRING: 9606.ENSP00000302289

UniGene: Hs.561411

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